DDR1-IN-1 clear

DDR1-IN-1 clearDDR1 IN 1 is a potent and selective discoidin domain receptor 1 (DDR1) receptor tyrosine kinase inhibitor with IC50 of 105 nM, about 3 fold selectivity over DDR2.

a natural enzyme

an alkaloid extracted from several plants

orally bioavailable

Cladribine is an adenosine deaminase inhibitor for U266

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4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase

Flavopiridol is initially found to inhibit EGFR and PKA

is a pentacyclic lupane-type triterpenoid naturally distributed in many plants and displays a broad spectrum of biological and pharmacological properties such as anticancer and chemopreventive activity

anti-vibration table

5 nM and 823

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which inhibits the early step in homologous recombination for double strand breaks repair