POLR2E rabbit monoclonal antibody package:50 μlSpecification Full name POLR2E rabbit monoclonal antibody Alternative names 50 l 100 l Reactivity rabbit monoclonal Applications WB, IHC Host Rabbit Clone type rabbit monoclonal Target Background This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA directed RNA polymerases and is present in two fold molar excess over the
Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism
Amplification and overexpression of this gene have been observed in several types of human carcinomas
Apr 2012] Swissprot No Q9UKT9 Gene Accession 22806 WB Predicted band size 58 kDa WB Positive control WB Recommended dilution 500-2000 IHC predicted cell location Predicted cell location: Nucleus IHC positive control Positive control: Human tonsil IHC Recommed dilution Recommended dilution: 50-100 Storage
possibly contributing to the functional diversity of the subunits
and as part of developmental regulation
Why do different suppliers show different activity or performance for PLX-3397
IHC Host Mouse Clone type mouse monoclonal Target Background This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria
Each unit features a clear polystyrene chamber mounted on a precision glass bottom with a polypropylene holder for secure handling
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The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells
Expression of this gene is induced by TGFBR1
The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'
