Cabozantinib malate (XL184) 22x50mm

Cabozantinib malate (XL184) 22x50mmCabozantinib malate (XL184) is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0. 035 nM and also inhibits c Met, Ret, Kit, Flt 1 3 4, Tie2, and AXL with IC50 of 1. 3 nM, 4 nM, 4. 6 nM, 12 nM 11. 3 nM 6 nM, 14. 3 nM and 7 nM in cell free assays, respectively.

inhibits NF-

good selectivity over related acyltransferases

reduces phosphorylation of pAktS473

B kinase (IKK) inhibitor for IKK-2

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Maximum capacity [Max]: 6 / 21g

M for the inhibition of proteasome and calpain

Elesclomol (STA-4783) is a novel potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells

such as experimental antitumor agents

095 for the inhibition of porcine H+

-Withstands a maximum RCF of 17

SB742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9